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Poverty plays growing role in major amputation risk
Major lower extremity amputations were once heavily concentrated in a narrow band of under-resourced, safety-net hospitals. A three-decade national study now shows that burden has spread well beyond those settings and that poverty is a more powerful predictor of limb…
Alcohol use disorder linked to higher rates of amputation and death after revascularization for CLTI
Alcohol use disorder (AUD) independently raises the risk of major adverse limb events (MALE) and mortality among patients undergoing lower-extremity revascularization for chronic limb-threatening ischemia (CLTI), according to a retrospective cohort study published in the Journal of Vascular Surgery (JVS).…
Biological sex remains a key determinant in CLTI revascularization rates and outcomes
Female patients had fewer endovascular revascularizations for chronic limb-threatening ischemia (CLTI) compared to male patients but experienced lower risks of mortality and major amputation, according to recent data. However, the findings also showed female patients were more likely to experience…
Premature PAD tied to higher amputation rates
Patients with premature peripheral arterial disease (PAD) face a significantly increased risk of mid- and late-term major amputation, according to a new analysis of the linked Vascular Quality Initiative and Medicare dataset (VQI-VISION). The research was presented at the 2026…
The intersection of palliative care and vascular surgery
As vascular surgeons, we strive to practice comprehensive vascular surgery care. This entails the medical and surgical management of patients with a wide range of vascular diagnoses. Patients with advanced vascular disease experience significantly reduced quality of life and high…
Designated multispecialty CLTI teams may help in amputation fight
Teams formally defined as specializing in chronic limb-threatening ischemia (CLTI) were associated with a decreased risk of major amputation among a subset of BEST-CLI trial sites, a paper recently published online ahead of print in the Journal of Vascular Surgery…
Multidisciplinary approach to diabetic foot ulcers in rural America leads to NIH grant
Samantha Minc, MD, MPH, associate professor of surgery at Duke University, has been awarded a National Institutes of Health (NIH) R03 grant to support her research project, “Understanding diabetes and peripheral arterial disease [PAD]-related amputation in North Carolina.” The R03…
SVS Highway to Health campaign aims to make PAD a household term
The Society for Vascular Surgery (SVS) is ramping up its national Highway to Health campaign to educate the public about peripheral arterial disease (PAD) and the importance of early detection as part of September’s PAD Awareness Month. Anahita Dua, MD,…
SWEDEPAD re-opens paclitaxel safety discussion, finds drug-coated devices do not improve outcomes
Drug-coated balloons and stents were not associated with reduced risk of amputation or improved quality of life compared with uncoated devices in the SWEDEPAD 1 and 2 trials. In addition, higher five-year mortality with drug-coated devices in patients with intermittent…
First patient enrolled in AngioDynamics’ AMBITION BTK trial for CLTI
AngioDynamics today announced enrollment of the first patient in AMBITION BTK, a randomized study of the Auryon atherectomy system in patients with below-the-knee chronic limb-threatening ischemia (CLTI). A press release details that AMBITION BTK is a prospective, multicenter, randomized controlled…