CEA found to significantly improve neurocognitive function 30 days after procedure

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Revascularization by way of carotid artery endarterectomy (CEA) is linked to significant improvements in neurocognitive function a month post- procedure across multiple domains, a July 1 scientific session will hear.

Furthermore, presenting author Natalie Sridharan, MD, assistant professor of surgery at the University of Pittsburgh Medical Center in Pittsburgh, Pennsylvania, will tell attendees about how statin use may provide further protection and that longer-term follow-up is needed “to see the magnitude and durability of these cognitive improvements.”

Sridharan et al made the discoveries during an interim noncomparative analysis of a cohort enrolled in an institutional randomized trial looking at the role of remote ischemic preconditioning for CEA.

The study was set against the backdrop of the rarity of stroke following CEA but the much more common occurrence of magnetic resonance imaging showing “silent” microinfarctions after surgery.

Some 80 patients with a mean age of 71.3 (± 7.1) were enrolled, the authors note.

In summing up their findings, they write: “Neurocognitive improvement following CEA may justify reconsideration of the role of carotid revascularization in asymptomatic patients.”

WHEN: Wednesday, July 1, 2020, 6:39 p.m.–6:51 p.m. Scientific Session 7

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