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Research indicates low stroke risk and benefit of medication alone in asymptomatic carotid stenosis
The risk of having a future stroke caused by asymptomatic carotid stenosis is “so low” that most patients with this condition could potentially be treated with the newest medications and may not require surgery. That is according to new research from Kaiser…
VentureMed completes enrollment of Flex Vessel Prep system randomized controlled trial in arteriovenous fistulas
VentureMed Group recently announced that it has completed enrollment of a randomized controlled trial (RCT) entitled “Flex Vessel Prep prior to PTA for the treatment of obstructive lesions in the native AVF.” This RCT was conducted to assess primary patency…
Interview: Combating the problem of spin, or overinterpretation, in RCTs
The presence of spin, or overinterpretation, in scientific papers that ultimately demonstrate statistically insignificant findings had been gnawing away at Thomas Forbes, MD, for quite some time. The practice, the University of Toronto vascular chair reflects, is by no means…
Canadian Vascular: Spin in RCTs
A large proportion of statistically nonsignificant randomized controlled trials (RCTs) yielded interpretations that were inconsistent with their results, according to an analysis of 31 manuscripts covering research comparing carotid endarterectomy (CEA) to carotid artery stenting (CAS) for carotid stenosis and…
High level of heterogeneity found in randomized PAD trial antithrombotic regimens
A recent systematic review showed that randomized trials comparing different types of peripheral endovascular arterial intervention have a high level of heterogeneity in their antithrombotic regimens. It also revealed an increasing trend for use of dual antiplatelet therapy post intervention…